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Scientists think they are a step closer to
a new drug *. More than two hundred million people suffer from this parasitic
worm disease. Mostly in developing nations inlamical climates. About ten
percent of victims became seriously disabled for internal bleeding, eye loss, organ
damage or other effects. A team in the United States has found a chemical
compuns known as dimicals can * in the enzyme needed for the survival of *soma.
This is the group of flat worms that cause *. The scientists tested * on laboratory
mice. They found that one compound killed the parasite at every level of development
from larva to adult. The study also shown that the compound with active against
all three major sbises of * worms that infect humans. The National Institute of
Health supported the research. Scientists from * University and Chemical Genomit Center
* reported the findings in the journal nature medicine. Biology professor,
David Williams, lend the research. He says *soma parasite needs oxygen to
survive.
参考
Scientists think they are a step closer to a new drug to
treat schistosomiasis. More than two hundred million people suffer from this
parasitic worm disease. Most live in developing nations in tropical climates.
About ten percent of victims become seriously disabled from internal bleeding,
iron loss, organ damage or other effects.
A team in the United
States found that chemical compounds known
as oxadiazoles can target an enzyme needed for the survival of Schistosoma.
This is the group of flatworms that cause schistosomiasis.
The scientists tested oxadiazoles on laboratory mice. They found that one
compound killed the parasite at every level of development – from larva to
adult. The study also showed that the compound was active against all three
major species of Schistosoma worms that infect humans.
The National Institutes of Health supported the research. Scientists from Illinois State
University and the Chemical Genomics
Center at N.I.H. reported
their findings in the journal Nature Medicine. Biology professor David Williams
led the research. He says the Schistosoma parasite needs oxygen to survive.
posted @ 2008-04-01 20:28
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